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Steven E Coutre Selected Research

idelalisib

10/2020Impact of idelalisib on health-related quality of life in patients with relapsed chronic lymphocytic leukemia in a phase III randomized trial.
11/2019Utility of positron emission tomography-computed tomography in patients with chronic lymphocytic leukemia following B-cell receptor pathway inhibitor therapy.
1/2019Final Results of a Randomized, Phase III Study of Rituximab With or Without Idelalisib Followed by Open-Label Idelalisib in Patients With Relapsed Chronic Lymphocytic Leukemia.
9/2018Pathological assessment of gastrointestinal biopsies from patients with idelalisib-associated diarrhea and colitis.
6/2018Idelalisib in Combination With Rituximab or Bendamustine or Both in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia.
12/2016Combinations of idelalisib with rituximab and/or bendamustine in patients with recurrent indolent non-Hodgkin lymphoma.
12/2015A phase 2 study of idelalisib plus rituximab in treatment-naïve older patients with chronic lymphocytic leukemia.
12/2015Idelalisib-associated Enterocolitis: Clinicopathologic Features and Distinction From Other Enterocolitides.
5/2014A phase 1 study of the PI3Kδ inhibitor idelalisib in patients with relapsed/refractory mantle cell lymphoma (MCL).
5/2014Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110δ, for relapsed/refractory chronic lymphocytic leukemia.
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Steven E Coutre Research Topics

Disease

22B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
10/2020 - 09/2002
7Diarrhea
01/2019 - 10/2013
6Neoplasms (Cancer)
01/2019 - 06/2007
5Infections
05/2022 - 09/2002
5Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2019 - 06/2007
4Colitis
01/2019 - 12/2015
4Leukemia
01/2019 - 06/2007
3Disease Progression
01/2022 - 07/2009
3Neutropenia
01/2019 - 12/2016
3Fatigue
01/2019 - 10/2013
3Pneumonia (Pneumonitis)
01/2019 - 05/2014
3Exanthema (Rash)
01/2018 - 05/2014
3Fever (Fevers)
05/2014 - 09/2002
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
11/2013 - 11/2008
2Febrile Neutropenia
01/2020 - 01/2011
2Lymphadenopathy
11/2019 - 05/2014
2Hemorrhage
01/2019 - 01/2019
2Lymphoid Leukemia
10/2018 - 12/2015
2Graft vs Host Disease (Graft-Versus-Host Disease)
12/2016 - 12/2015
2Thrombocytopenia (Thrombopenia)
10/2013 - 08/2007
2Multiple Myeloma
10/2013 - 07/2009
2Hypereosinophilic Syndrome (Loeffler Endocarditis)
05/2003 - 03/2003
1COVID-19
05/2022
1Respiratory Insufficiency (Respiratory Failure)
05/2022
1Hyperglycemia
01/2020
1Hypoxia (Hypoxemia)
01/2020
1Headache (Headaches)
01/2020
1Hypertension (High Blood Pressure)
01/2019
1Philadelphia Chromosome
10/2018
1Residual Neoplasm
12/2016
1Non-Hodgkin Lymphoma (Lymphosarcoma)
12/2016
1Enterocolitis
12/2015
1Inflammation (Inflammations)
12/2015
1Autoimmune enteropathy
12/2015
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
12/2015
1Nausea
05/2014
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
05/2014
1Hemolytic Anemia
08/2007
1Renal Insufficiency (Renal Failure)
08/2007
1Thrombotic Thrombocytopenic Purpura
08/2007
1Endometrial Neoplasms (Endometrial Cancer)
08/2007
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
06/2007
1Amyloidosis
05/2006
1Hematuria
05/2006
1Chromosome Aberrations (Chromosome Abnormalities)
03/2003

Drug/Important Bio-Agent (IBA)

17ibrutinibIBA
05/2022 - 07/2013
11idelalisibIBA
10/2020 - 03/2014
8Rituximab (Mabthera)FDA Link
01/2019 - 09/2002
6Agammaglobulinaemia Tyrosine KinaseIBA
01/2020 - 10/2016
3Dexamethasone (Maxidex)FDA LinkGeneric
05/2022 - 07/2009
3Pharmaceutical PreparationsIBA
10/2016 - 07/2009
2Alanine Transaminase (SGPT)IBA
01/2020 - 05/2014
2Chlorambucil (Leukeran)FDA Link
01/2020 - 11/2018
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2020 - 05/2014
2venetoclaxIBA
11/2019 - 11/2019
2Transaminases (Aminotransferases)IBA
01/2019 - 12/2016
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2019 - 11/2018
2fludarabineIBA
01/2019 - 11/2018
2Vincristine (Oncovin)FDA LinkGeneric
10/2018 - 01/2012
2Bendamustine HydrochlorideFDA Link
06/2018 - 12/2016
2Tyrosine Kinase InhibitorsIBA
01/2017 - 05/2003
2Phosphotransferases (Kinase)IBA
12/2016 - 05/2014
2Imatinib Mesylate (Gleevec)FDA Link
05/2003 - 03/2003
2Alemtuzumab (Campath)FDA Link
02/2003 - 09/2002
1remdesivirIBA
05/2022
1Oxygen (Dioxygen)IBA
05/2022
1Biological ProductsIBA
11/2019
1Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
11/2019
1AnticoagulantsIBA
01/2019
1ofatumumabFDA Link
11/2018
1serum P-component (CIt)IBA
11/2018
1Liposomes (Liposome)IBA
10/2018
1Interleukin-2 (IL2)IBA
12/2016
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
12/2015
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
05/2014
1LipidsIBA
05/2014
1Azacitidine (5 Azacytidine)FDA Link
11/2013
1Gemtuzumab (Mylotarg)FDA Link
11/2013
1Hydroxyurea (Hydrea)FDA LinkGeneric
11/2013
1PanobinostatIBA
10/2013
1Bortezomib (Velcade)FDA Link
10/2013
1Immunoglobulin M (IgM)IBA
01/2012
1Monoclonal AntibodiesIBA
01/2012
1Temozolomide (Temodar)FDA LinkGeneric
01/2012
1lactosamineIBA
01/2012
1AntigensIBA
01/2012
1Lenalidomide (CC 5013)FDA Link
07/2009
1thiamine triphosphorate (TTP)IBA
08/2007
1nelarabine (506U78)FDA Link
06/2007
1Factor X (Stuart Factor)IBA
05/2006
1Factor VII (Proconvertin)IBA
05/2006
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
03/2003
1Platelet-Derived Growth Factor alpha ReceptorIBA
03/2003

Therapy/Procedure

18Therapeutics
05/2022 - 09/2002
4Drug Therapy (Chemotherapy)
11/2019 - 03/2014
2Splenectomy
05/2006 - 09/2002
1Drug Tapering
01/2019
1Cell Transplantation
01/2017
1Hysterectomy
08/2007
1Lymph Node Excision (Lymph Node Dissection)
08/2007